par- 23 février 2013
Deputy-director of the Lyon Neuroscience Research Center (CRNL)
Head of the Phd Program "Neuroscience and Cognition"
Téléphone : + 33 (0)4 37 28 76 00
Cross-modal olfacto-tactile memory circuits
In rodent, most studies devoted to the understanding of neural bases supporting learning and memory rely on behavioral paradigms in which animals have to take into account one category of sensory cues (auditory, olfactory, visual). However real objects have several dimensions (shape, color, texture...). We dont know much of network and mechanisms supporting association of these different dimensions. We have developed a new behavioral paradigm in rats in which they have to recognize objects both on the basis of their olfactory and texture dimensions. We are trying to identify neural structures involved in the formation, recall and flexibility of olfactory-pired associated. We are particularly exploring the role of the lateral entorhinal cortex and the dorsal hippocampus. For exemple, we have shown that the lateral entorhinal cortex is critically involved in the formation of olfacto-tactile associations but not in their recall1.
1Boisselier L, Ferry B, Gervais, R .(2014) Involvement of the lateral entorhinal cortex for the formation of the cross-modal olfactory-tactile associations in the rat. Hippocampus, Apr 9. doi:10.1002/hipo.22277.
Voir en ligne : PhD Program Neuroscience and cognition