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Equipes de recherche
Equipe CMO (N.Ravel, N.Buonviso)
- 29 janvier 2014
Chargé de Recherche CNRS
Bureau : 105
Téléphone : + 33 (0)4 37 28 74 xx
Fax : +33 (0)4 37 28 76 01
e-mail : Barbara.Ferry[at]cnrs.fr
The main issue of my research is based on the identification of the operating dynamics of neural networks involved in the processes underlying olfactory memory in the rodent. In particular, our studies aim at evidencing the behavioral, pharmacological and molecular mechanisms that control olfactory memory formation during associative learning in the rat, with a particular emphasis on the noradrenergic system of particular structures in the CNS.
To this aim, we use different behavioral paradigms such as the conditioned odor aversion or preference that are based on the association between an odor and an unconditioned stimulus (of negative or positive hedonic values).
Our first concern is the role of the noradrenergic system in the structures involved in the first (olfactory bulb) and higher level (entorhinal cortex, amygdala) of olfactory processing, in the mechanisms underlying olfactory learning and memory.
Our second research interest focuses on the role of the hippocampus and the entorhinal cortex in the associative mechanisms underlying the bimodal olfactory-tactile task. In particular, we will study the involvement of the cholinergic and glutamatergic systems in these structures during the acquisition and the flexibility of the task.
The third area we are interested in is the role of the orexin peptide in the processes underlying the olfactory short-term memory. Indeed, recent results have shown that this peptide, largely involved in the food intake regulation, seems also to be involved in the modulation of the olfactory memory, via an influence of the olfactory bulb and the amygdala activity.