par- 5 février 2014
Office : 221
Research Associate, Centre de Neurosciences Paris-Sud (CNPS), CNRS UMR8195, Université Paris-Sud XI, Orsay
The main objective of my research is to identify mechanisms of plasticity in the adult brain that underlie memory. Using rodent models (rats and transgenic mice), I previously asked how different key mechanisms of plasticity, such as noradrenalin, Collapsin Response Mediator Proteins, estrogens, the Immediate Early Gene Zif268/Egr1 and the formation of new neurons in the adult olfactory bulb and hippocampus, contribute to specific phases and processes of memory (learning, recall and consolidation).
Technical Skills :
-Surgery : stereotaxic injection of viral vectors, implantation for chronic hormonal treatment, olfactory sensory deprivations
-Behavior : episodic-like memory, spatial learning radial and water maze, perceptual olfactory learning, non-associative olfactory memory, olfactory passive stimulation, socio-sexual behavior, olfactory and environmental enrichment, locomotion behavior
-Pharmacology : acute and chronic treatment of noradrenergic agents
-Cellular and Molecular Biology : Immunohistochemistry, HIS, RT-PCR, Western Blotting, adult neural stem cells culture, viral and non-viral cell transfection, design of siRNA
-Imaging analysis : Optical and Confocal microscopy (Leica, Zeiss, Olympus), brain stereology
2005 : PhD in Neuroscience, Laboratoire Neurosciences Systèmes Sensoriels, University Lyon. Molecular and cellular mechanisms of neurogenesis regulation in the adult mouse olfactory system.
2007-2008 : Post-doc Dipartimento di Biologia Animale e dell’Uomo, University Turin, Italy.
2008-2009 : Post-doc Cellular and Molecular Neurobiology Center, University Liège, Belgium.
2009-2013 : Post-doc Centre de Neurosciences Paris-Sud, University Paris-Sud XI, Orsay.
2000-2006 : Teaching lecturer Licence, Master Physiology and Neuroscience, University Lyon (292h)